Akt1 and Akt2-IN-1
Catalog No: 611804
CAS Number: 893422-47-4
Purity: 98%
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50 = 3.5 nM) and Akt2 (IC50 = 42 nM), with potent and balanced activity. Akt1 and Akt2-IN-1 has moderate activity in an hERG binding assay (IC50 = 5610 nM) and is a substrate for human P-glycoprotein (MDR1 Directional Transport Ratio (B to A/A to B) = 17.6). Akt1 and Akt2-IN-1 also shows good physical properties with a human plasma protein binding of 97.3% and a logP = 3.51.
For research use only. We do not sell to patients.
Chemical Information
| Name | Akt1 and Akt2-IN-1 |
|---|---|
| Synonyms | Akt1 and Akt2-IN-1 |
| Molecular Formula | C33H29N7O |
| Molecular Weight | 539.63 |
| Smile | c1ccc(cc1)c2cc3c(cc[nH]c3=O)nc2c4ccc(cc4)CN5CCC(CC5)c6nc([nH]n6)c7ccccn7 |
| InChiKey | BTUWHHFNOHVCMQ-UHFFFAOYSA-N |
| InChi | InChI=1S/C33H29N7O/c41-33-27-20-26(23-6-2-1-3-7-23)30(36-28(27)13-17-35-33)24-11-9-22(10-12-24)21-40-18-14-25(15-19-40)31-37-32(39-38-31)29-8-4-5-16-34-29/h1-13,16-17,20,25H,14-15,18-19,21H2,(H,35,41)(H,37,38,39) |
| CAS Number | 893422-47-4 |
| MDL | MFCD13184803 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
