Abdenoflast (VTX2735) is a small-molecule, non-steroidal inhibitor of the NLRP3 inflammasome with anti-inflammatory activity.
For research use only. We do not sell to patients.
| Name | Abdenoflast |
|---|---|
| Iupac Chemical Name | N-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-4,6,7,8-tetrahydro-5,8-ethanofuro[3,2-c]azepine-2-sulfonamide |
| Synonyms | Abdenoflast ; VTX2735 ; VTX 2735 ; VTX-2735 |
| Molecular Formula | C23H27N3O4S |
| Molecular Weight | 441.5 |
| Smile | O=S(C(O1)=CC2=C1C(CC3)CCN3C2)(NC(NC4=C5CCCC5=CC6=C4CCC6)=O)=O |
| InChiKey | LQKIQSJLXCYGOX-UHFFFAOYSA-N |
| InChi | InChI=1S/C23H27N3O4S/c27-23(24-21-18-5-1-3-15(18)11-16-4-2-6-19(16)21)25-31(28,29)20-12-17-13-26-9-7-14(8-10-26)22(17)30-20/h11-12,14H,1-10,13H2,(H2,24,25,27) |
| CAS Number | 2712741-60-9 |
| Related CAS | 2712741-60-9 |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |