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AZD2858

Catalog No.: 122838
Cas No.: 486424-20-8
Purity : 98% 

AZD2858 is a selective GSK-3 inhibitor with an IC50 of 68 nM, inhibits tau phosphorylation at the S396 site, activates Wnt signaling pathway. 

For research use only. We do not sell to patients.

Chemical Information

NameAZD2858
Iupac Chemical Name3-amino-6-[4-(4-methylpiperazin-1-yl)sulfonylphenyl]-N-pyridin-3-ylpyrazine-2-carboxamide 
SynonymsAZD 2858; AZD-2858 
Molecular FormulaC21H23N7O3S 
Molecular Weight453.517 
SmileCN1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)C3=CN=C(C(=N3)C(=O)NC4=CN=CC=C4)N
InChiKeyFHCSBLWRGCOVPT-UHFFFAOYSA-N
InChiInChI=1S/C21H23N7O3S/c1-27-9-11-28(12-10-27)32(30,31)17-6-4-15(5-7-17)18-14-24-20(22)19(26-18)21(29)25-16-3-2-8-23-13-16/h2-8,13-14H,9-12H2,1H3,(H2,22,24)(H,25,29)
CAS Number486424-20-8
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

122838 - AZD2858 | CAS 486424-20-8

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