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AZ304

Catalog No.: 19363
Cas No.: 942507-42-8
Purity : >98%
19363 - AZ304  | CAS 942507-42-8

Catalog number : 19363

CAS number : 942507-42-8

Molecular Formula : C27H25N5O2

Molecular Weight : 451.52

Chemical Name : AZ304

Smile : O=C(NC1=CC=C(C)C(NC2=C3C=CC(OC)=CC3=NC=N2)=C1)C4=CC=CC(C(C)(C#N)C)=C4

InChiKey :

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SynonymsAZ304;AZ 304;AZ-304.
Molecular FormulaC27H25N5O2
Molecular Weight451.52
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileO=C(NC1=CC=C(C)C(NC2=C3C=CC(OC)=CC3=NC=N2)=C1)C4=CC=CC(C(C)(C#N)C)=C4
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AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC50s of 79 nM, 38 nM and 68 nM, respectively.

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