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AZ304 Catalog No : 19363

Chemical Information

Product NameAZ304
SynonymsAZ304;AZ 304;AZ-304.
Molecular FormulaC27H25N5O2
Molecular Weight451.52
SmileO=C(NC1=CC=C(C)C(NC2=C3C=CC(OC)=CC3=NC=N2)=C1)C4=CC=CC(C(C)(C#N)C)=C4
InChiKey
InChi
Cas942507-42-8

Technical Data

AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
Quality control

Description

AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC50s of 79 nM, 38 nM and 68 nM, respectively.

Chemical Structure

19363 - AZ304  | CAS 942507-42-8

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