AV-412
Catalog No: 112101
CAS Number: 451492-95-8
Purity: 99.38%
AV-412 is an EGFR/HER2 inhibitor that binds to and inhibits the epidermal growth factor receptor (EGFR) and the human epidermal growth factor receptor 2 (HER2), which may result in the inhibition of tumor growth and angiogenesis.
AV-412(Free base) and AV-412 Tosylate, Bulk in stock, contact us by email for the bulk quotation.
For research use only. We do not sell to patients.
Chemical Information
| Name | AV-412 |
|---|---|
| Iupac Chemical Name | N-(4-((3-chloro-4-fluorophenyl)amino)-7-(3-methyl-3-(4-methylpiperazin-1-yl)but-1-yn-1-yl)quinazolin-6-yl)acrylamide |
| Synonyms | AV412 ; AV 412; MP412; MP-412 |
| Molecular Formula | C27H28ClFN6O |
| Molecular Weight | 507.00 |
| Smile | C=CC(NC1=CC2=C(NC3=CC=C(F)C(Cl)=C3)N=CN=C2C=C1C#CC(N4CCN(C)CC4)(C)C)=O |
| InChiKey | ZAJXXUDARPGGOC-UHFFFAOYSA-N |
| InChi | InChI=1S/C27H28ClFN6O/c1-5-25(36)33-23-16-20-24(30-17-31-26(20)32-19-6-7-22(29)21(28)15-19)14-18(23)8-9-27(2,3)35-12-10-34(4)11-13-35/h5-7,14-17H,1,10-13H2,2-4H3,(H,33,36)(H,30,31,32) |
| CAS Number | 451492-95-8 |
| Related CAS | 451493-31-5 ( AV-412 Tosylate ) |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | light-yellow solid |
|---|---|
| Purity | 99.38% |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
