ATH434 mesylate
Catalog No: 20638
CAS Number: 2387898-69-1
Purity: ≧98.0%
ATH434, is an oral agent designed to inhibit the aggregation of pathological proteins implicated in neurodegeneration. ATH434 has been shown preclinically to reduce α-synuclein pathology and preserve neuronal function by restoring normal iron balance in the brain.
For research use only. We do not sell to patients.
Chemical Information
| Name | ATH434 mesylate |
|---|---|
| Iupac Chemical Name | 5,7-dichloro-2-(ethylaminomethyl)-8-hydroxy-3-methylquinazolin-4-one, methanesulfonic acid |
| Synonyms | PBT434 ; PBT 434 ; PBT-434 ; ATH434 ; ATH 434 ; ATH-434 |
| Molecular Formula | C13H17Cl2N3O5S |
| Molecular Weight | 398.3 |
| Smile | O=C1N(C)C(CNCC)=NC2=C1C(Cl)=CC(Cl)=C2O.CS(=O)(O)=O |
| InChiKey | UBTJWJNTOFSHON-UHFFFAOYSA-N |
| InChi | InChI=1S/C12H13Cl2N3O2.CH4O3S/c1-3-15-5-8-16-10-9(12(19)17(8)2)6(13)4-7(14)11(10)18;1-5(2,3)4/h4,15,18H,3,5H2,1-2H3;1H3,(H,2,3,4) |
| CAS Number | 2387898-69-1 |
| Related CAS | 2387898-69-1 |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
