ARN14494 is a Selective Serine Palmitoyltransferase (SPT) Inhibitor which is a key enzyme of sphingolipid metabolism.
For research use only. We do not sell to patients.
Name | ARN14494 |
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Iupac Chemical Name | 1-(1-(2-((3aR,6aS)-hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-2-oxoethyl)piperidin-4-yl)-N-methyl-2-oxoindoline-5-carboxamide |
Synonyms | ARN14494 ; ARN 14494 ; ARN-14494 |
Molecular Formula | C24H32N4O3 |
Molecular Weight | 424.55 |
Smile | O=C(C1=CC2=C(N(C3CCN(CC(N4C[C@]5([H])[C@](CCC5)([H])C4)=O)CC3)C(C2)=O)C=C1)NC |
InChiKey | TYZOOEYUTZDYPB-HDICACEKSA-N |
InChi | InChI=1S/C24H32N4O3/c1-25-24(31)16-5-6-21-19(11-16)12-22(29)28(21)20-7-9-26(10-8-20)15-23(30)27-13-17-3-2-4-18(17)14-27/h5-6,11,17-18,20H,2-4,7-10,12-15H2,1H3,(H,25,31)/t17-,18+ |
CAS Number | 1037837-27-6 |
Related CAS | 1037837-27-6 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | SPT inhibitor |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |