Welcome to Sun-shine chemical
+86-27-65522453 sales@sun-shinechem.com

Netarsudil (AR-13324) 2HCl

Catalog No.: 1710901
Cas No.: 1253952-02-1
Purity : 98% 

Netarsudil (a.k.a. AR-13324) is ROCK inhibitor with Ki value of 0.2-10.3 nM. It is currently in clinical trials for the treatment of glaucoma and ocular hypertension. 

For research use only. We do not sell to patients.

Chemical Information

NameNetarsudil (AR-13324) 2HCl
Iupac Chemical Name(S)-4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate dihydrochloride
SynonymsNetarsudil; Netarsudil hydrochloride; AR-13324 HCl; AR-13324 HCl; AR13324 HCl; AR13324 HCl
Molecular FormulaC28H27N3O3.2HCl 
Molecular Weight526.45 
SmileO=C(OCC1=CC=C([C@@H](CN)C(NC2=CC3=C(C=NC=C3)C=C2)=O)C=C1)C4=CC=C(C)C=C4C.[H]Cl.[H]Cl
InChiKeyLDKTYVXXYUJVJM-FBHGDYMESA-N
InChiInChI=1S/C28H27N3O3.2ClH/c1-18-3-10-25(19(2)13-18)28(33)34-17-20-4-6-21(7-5-20)26(15-29)27(32)31-24-9-8-23-16-30-12-11-22(23)14-24;;/h3-14,16,26H,15,17,29H2,1-2H3,(H,31,32);2*1H/t26-;;/m1../s1
CAS Number1253952-02-1
Related CAS1422144-42-0 (mesylate) 1254032-66-0 (free base) 1253952-02-1 (HCl)

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
BulkEnquiryEnquiryEnquiry
Request Bulk Quote Download MSDS Tel : +86-27-65522453   Email : sales@sun-shinechem.com
FormulationOff-white solid to white solid
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

1710901 - Netarsudil (AR-13324) 2HCl | CAS 1253952-02-1

Quick inquiry

Change