AP1189 is a melanocortin receptor agonist on MC1 and MC3 receptors.
For research use only. We do not sell to patients.
名称 | AP1189 acetate |
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Iupac 化学名称 | (E)-N-[trans-3-{1-(2-Nitrophenyl)-1H-pyrrol-2-yl} allylidenamino]guanidinium acetate |
同义词 | AP-1189 ; AP 1189 ; AP1189 ; AP1189 acetate |
分子式 | C16H18N6O4 |
分子量 | 358.36 |
Smile | NC(N/N=C/C=C/C1=CC=CN1C2=CC=CC=C2[N+]([O-])=O)=N.CC(O)=O |
InChiKey | FIESOFUABUPMMH-WAJHRQJSSA-N |
InChi | InChI=1S/C14H14N6O2.C2H4O2/c15-14(16)18-17-9-3-5-11-6-4-10-19(11)12-7-1-2-8-13(12)20(21)22;1-2(3)4/h1-10H,(H4,15,16,18);1H3,(H,3,4)/b5-3+,17-9+; |
Cas号 | 959850-74-9 |
Related CAS | 959850-74-9 |
Packaging | 价格 | Availability | 纯度 | Shipping Time |
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Bulk | 询价 | 询价 | 询价 |
Formulation | Yellow Solid |
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纯度 | ≧98.0% |
存储 | Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years). |
可溶性 | Soluble in DMSO |
Handling | Avoid inhalation, contact with eyes and skin. Avoid dust and aerosol formation. Use only in areas with appropriate exhaust ventilation. |
运输条件 | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code |
Targets | |
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Mechanism | |
Cell study | |
Animal study | |
Clinical study |
1: Montero-Melendez T, Gobbetti T, Cooray SN, Jonassen TE, Perretti M. Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects. J Immunol. 2015 Apr 1;194(7):3381-8. doi: 10.4049/jimmunol.1402645. Epub 2015 Feb 27. PubMed PMID: 25725103.