AMX-883
Catalog No: 26A035
CAS Number:
Purity: ≧98.0%
Amx-883 is a potent and selective degrader of BRD9 drives differentiation in acute myeloid leukaemia.
For research use only. We do not sell to patients.
Chemical Information
| Name | AMX-883 |
|---|---|
| Iupac Chemical Name | (R,E)-2-(5-((7-(2,6-dimethoxy-4-(1,4,5-trimethyl-6-oxo-1,6-dihydropyridin-3-yl)benzyl)-4,7-diazaspiro[2.5]octan-4-yl)methyl)-1-isopropyl-7-methoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)-5-fluoro-4,4-dimethylpent-2-enenitrile |
| Synonyms | AMX-883 ; AMX 883 ; AMX883 |
| Molecular Formula | C45H58FN5O5 |
| Molecular Weight | 767.99 |
| Smile | CN1C=C(C2=CC(OC)=C(CN3CC4(CC4)N(CC5=C(CCN(C(/C(C#N)=C/C(C)(C)CF)=O)[C@@H]6C(C)C)C6=CC(OC)=C5)CC3)C(OC)=C2)C(C)=C(C)C1=O |
| InChiKey | CQFKKLHTDCRYTN-IHRRMNPYSA-N |
| InChi | InChI=1S/C45H58FN5O5/c1-28(2)41-36-20-34(54-8)17-32(35(36)11-14-51(41)43(53)33(22-47)21-44(5,6)26-46)23-50-16-15-49(27-45(50)12-13-45)25-38-39(55-9)18-31(19-40(38)56-10)37-24-48(7)42(52)30(4)29(37)3/h17-21,24,28,41H,11-16,23,25-27H2,1-10H3/b33-21+/t41-/m1/s1 |
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| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
