ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, safe and effective in the skeletal muscle.
For research use only. We do not sell to patients.
Name | ALT-007 |
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Iupac Chemical Name | N-(4-(5,6-dimethoxynicotinoyl)-1-isopropyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridin-7-yl)-2-(trifluoromethoxy)benzamide |
Synonyms | ALT-007 ; ALT 007 ; ALT 007 |
Molecular Formula | C25H26F3N5O5 |
Molecular Weight | 533.51 |
Smile | O=C(NC1C(N(C(C)C)N=C2)=C2N(C(C3=CN=C(OC)C(OC)=C3)=O)CC1)C4=CC=CC=C4OC(F)(F)F |
InChiKey | MOKGQUKWOUYHHS-UHFFFAOYSA-N |
InChi | InChI=1S/C25H26F3N5O5/c1-14(2)33-21-17(31-22(34)16-7-5-6-8-19(16)38-25(26,27)28)9-10-32(18(21)13-30-33)24(35)15-11-20(36-3)23(37-4)29-12-15/h5-8,11-14,17H,9-10H2,1-4H3,(H,31,34) |
CAS Number | 2035010-37-6 |
Related CAS | 2035010-37-6 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | SPT inhibitor |
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Mechanism | ALT-007, targeting the rate-limiting enzyme of ceramide de novo synthesis, serine palmitoyltransferase (SPT). |
Cell study | |
Animal study | |
Clinical study |