ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, safe and effective in the skeletal muscle. ALT-007 may enhance protein homeostasis in Caenorhabditis elegans and mouse models of aging and age-related diseases and play the role of a ceramide inhibitor.
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Name | ALT-007 |
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Iupac Chemical Name | N-(4-(5,6-dimethoxynicotinoyl)-1-isopropyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-b]pyridin-7-yl)-2-(trifluoromethoxy)benzamide |
Synonyms | ALT-007 ; ALT 007 ; ALT007 |
Molecular Formula | C25H26F3N5O5 |
Molecular Weight | 533.51 |
Smile | O=C(NC1C(N(C(C)C)N=C2)=C2N(C(C3=CN=C(OC)C(OC)=C3)=O)CC1)C4=CC=CC=C4OC(F)(F)F |
InChiKey | MOKGQUKWOUYHHS-UHFFFAOYSA-N |
InChi | InChI=1S/C25H26F3N5O5/c1-14(2)33-21-17(31-22(34)16-7-5-6-8-19(16)38-25(26,27)28)9-10-32(18(21)13-30-33)24(35)15-11-20(36-3)23(37-4)29-12-15/h5-8,11-14,17H,9-10H2,1-4H3,(H,31,34) |
CAS Number | 2035010-37-6 |
Related CAS | 2035010-37-6 |
Packaging | Price | Availability | Purity | Shipping Time |
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Bulk | Enquiry | Enquiry | Enquiry |
Formulation | Solid powder |
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Purity | ≧98.0% |
Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
Handling | Refer to MSDS |
Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
HS Code | 2934200090 |
Targets | SPT inhibitor |
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Mechanism | ALT-007 is an orally bioavailable SPT inhibitor that is more potent than myriocin, safe and effective in the skeletal muscle. ALT-007 may enhance protein homeostasis in Caenorhabditis elegans and mouse models of aging and age-related diseases and play the role of a ceramide inhibitor. |
Cell study | |
Animal study | |
Clinical study |