AF710B is a highly selective and potent allosteric agonist for M1 muscarinic and σ1 receptors. It can be used in research on Alzheimer's disease.
For research use only. We do not sell to patients.
| Name | AF710B |
|---|---|
| Iupac Chemical Name | (S)-1-(2,8-dimethyl-1-thia-3,8-diazaspiro[4.5]decan-3-yl)-3-(1H-indol-3-yl)propan-1-one |
| Synonyms | AF710B |
| Molecular Formula | C20H27N3OS |
| Molecular Weight | 357.51 |
| Smile | O=C(N1[C@H](C)SC2(CCN(C)CC2)C1)CCC3=CNC4=CC=CC=C43 |
| InChiKey | XWMHYQATSBWUNT-HNNXBMFYSA-N |
| InChi | InChI=1S/C20H27N3OS/c1-15-23(14-20(25-15)9-11-22(2)12-10-20)19(24)8-7-16-13-21-18-6-4-3-5-17(16)18/h3-6,13,15,21H,7-12,14H2,1-2H3/t15-/m0/s1 |
| CAS Number | N/A |
| Related CAS | 1235733-73-9 ( Rac ) |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white to light-yellow solid |
|---|---|
| Purity | ≧98.0% ; EE≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code | 2934200090 |
| Targets | Agonist for M1 muscarinic and σ1 receptors |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |