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AF-615

Catalog No: 24135
CAS Number: 122510-61-6
Purity: 98% Min.

AF-615 is a novel Inhibitor of CDT1/Geminin Protein Complex, promoting DNA Damage and Cell Death in Cancer Cells

For research use only. We do not sell to patients.

Chemical Information

NameAF-615
Iupac Chemical NameN'-(morpholine-4-carbonothioyl)pyrazine-2-carbohydrazide
SynonymsAF-615; AF615; AF 615
Molecular FormulaC10H13N5O2S
Molecular Weight267.31
SmileO=C(C1=NC=CN=C1)NNC(N2CCOCC2)=S
InChiKeyMVIKQAFXLHULLI-UHFFFAOYSA-N
InChiInChI=1S/C10H13N5O2S/c16-9(8-7-11-1-2-12-8)13-14-10(18)15-3-5-17-6-4-15/h1-2,7H,3-6H2,(H,13,16)(H,14,18)
CAS Number122510-61-6
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Ordering Information

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Formulation类白色固体
Purity98% Min.
Storage 0-4℃,可保存几天到几周;-20℃,可保存 几个月。
Solubility溶于DMSO等有机溶剂
Handling
Shipping Condition可以在室温下进行运输。
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study

1) Nikolaos Karantzelis et al. Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells; Front Pharmacol. 2022; 13: 860682.

Chemical Structure

24135 - AF-615 | CAS 122510-61-6

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