AF-615
Catalog No: 24135
CAS Number: 122510-61-6
Purity: 98% Min.
AF-615 is a novel Inhibitor of CDT1/Geminin Protein Complex, promoting DNA Damage and Cell Death in Cancer Cells
For research use only. We do not sell to patients.
Chemical Information
| Name | AF-615 |
|---|---|
| Iupac Chemical Name | N'-(morpholine-4-carbonothioyl)pyrazine-2-carbohydrazide |
| Synonyms | AF-615; AF615; AF 615 |
| Molecular Formula | C10H13N5O2S |
| Molecular Weight | 267.31 |
| Smile | O=C(C1=NC=CN=C1)NNC(N2CCOCC2)=S |
| InChiKey | MVIKQAFXLHULLI-UHFFFAOYSA-N |
| InChi | InChI=1S/C10H13N5O2S/c16-9(8-7-11-1-2-12-8)13-14-10(18)15-3-5-17-6-4-15/h1-2,7H,3-6H2,(H,13,16)(H,14,18) |
| CAS Number | 122510-61-6 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid |
|---|---|
| Purity | 98% Min. |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
1) Nikolaos Karantzelis et al. Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells; Front Pharmacol. 2022; 13: 860682.
Chemical Structure
