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AEE788

Catalog No.: 52750
Cas No.: 497839-62-0
Purity : 98% 

AEE788(NVP-AEE 788) is a potent inhibitor of EGFR and HER2/ErbB2 with IC50 of 2 nM and 6 nM, less potent to VEGFR2/KDR, c-Abl, c-Src, and Flt-1, does not inhibit Ins-R, IGF-1R, PKC and CDK1. 

For research use only. We do not sell to patients.

Chemical Information

NameAEE788
Molecular FormulaC27H32N6 
Molecular Weight440.58 
SmileCCN1CCN(CC1)Cc2ccc(cc2)c3cc-4c(nc[nH]c4n3)N[C@H](C)c5ccccc5
InChiKeyFZKTWZZPPTUYSG-GQJKKZBQSA-N
InChiInChI=1S/C27H40N6/c1-3-32-13-15-33(16-14-32)18-21-9-11-23(12-10-21)25-17-24-26(28-19-29-27(24)31-25)30-20(2)22-7-5-4-6-8-22/h4-12,20,24-31H,3,13-19H2,1-2H3/t20-,24?,25?,26?,27?/m1/s1
CAS Number497839-62-0
MDLMFCD11100351
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Ordering Information

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Purity98% 
SolubilityDMSO 88 mg/mL; Water <1 mg/mL; Ethanol <1 mg/mL 
Handling
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

52750 - AEE788 | CAS 497839-62-0

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