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ADX-47273

Catalog No.: 185173
Cas No.: 851881-60-2
Purity : >98%
185173 - ADX-47273  | CAS 851881-60-2

Catalog number : 185173

CAS number : 851881-60-2

Molecular Formula : C20H17F2N3O2

Molecular Weight : 369.37

Iupac Chemical Name : (S)-(4-fluorophenyl)(3-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone

Smile : O=C(C1=CC=C(F)C=C1)N2C[C@@H](C3=NC(C4=CC=C(F)C=C4)=NO3)CCC2

InChiKey : VXQCCZHCFBHTTD-HNNXBMFYSA-N

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SynonymsADX-47273; ADX 47273; ADX47273.
Molecular FormulaC20H17F2N3O2
Molecular Weight369.37
AppearanceOff-white solid to white solid
Purity>98%
SolubilitySoluble in DMSO
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature
SmileO=C(C1=CC=C(F)C=C1)N2C[C@@H](C3=NC(C4=CC=C(F)C=C4)=NO3)CCC2
InChiKeyVXQCCZHCFBHTTD-HNNXBMFYSA-N
InChiInChI=1S/C20H17F2N3O2/c21-16-7-3-13(4-8-16)18-23-19(27-24-18)15-2-1-11-25(12-15)20(26)14-5-9-17(22)10-6-14/h3-10,15H,1-2,11-12H2/t15-/m0/s1
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ADX-47273 is a potent and selective mGluR5 receptor PAM (positive allosteric modulator), EC50 = 0.17 μm, with no effect on other mGluR subtypes.

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