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ADX-47273

Catalog No: 185173
CAS Number: 851881-60-2
Purity: >98%

ADX-47273 is a potent and selective mGluR5 receptor PAM (positive allosteric modulator), EC50 = 0.17 μm, with no effect on other mGluR subtypes.

For research use only. We do not sell to patients.

Chemical Information

NameADX-47273
Iupac Chemical Name(S)-(4-fluorophenyl)(3-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone
SynonymsADX-47273; ADX 47273; ADX47273.
Molecular FormulaC20H17F2N3O2
Molecular Weight369.37
SmileO=C(C1=CC=C(F)C=C1)N2C[C@@H](C3=NC(C4=CC=C(F)C=C4)=NO3)CCC2
InChiKeyVXQCCZHCFBHTTD-HNNXBMFYSA-N
InChiInChI=1S/C20H17F2N3O2/c21-16-7-3-13(4-8-16)18-23-19(27-24-18)15-2-1-11-25(12-15)20(26)14-5-9-17(22)10-6-14/h3-10,15H,1-2,11-12H2/t15-/m0/s1
CAS Number851881-60-2
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

185173 - ADX-47273 | CAS 851881-60-2

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