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A-674563 Catalog No : 52617

Chemical Information

Product NameA-674563
Molecular FormulaC22H22N4O 
Molecular Weight358.44 
SmileCc1c2cc(ccc2[nH]n1)c3cc(cnc3)OC[C@H](Cc4ccccc4)N.Cl
InChiKeyHLNHYVLLEFHBJD-FYZYNONXSA-N
InChiInChI=1S/C22H22N4O.ClH/c1-15-21-11-17(7-8-22(21)26-25-15)18-10-20(13-24-12-18)27-14-19(23)9-16-5-3-2-4-6-16;/h2-8,10-13,19H,9,14,23H2,1H3,(H,25,26);1H/t19-;/m0./s1
Cas552325-73-2
MDLMFCD18711680

Technical Data

Purity98% 
Quality control

Description

A-674563 is a potent selective Akt1 inhibitor with an IC50 of 14 nM; also shows inhibitory activity against PKA and CDK2 with IC50 of 16 and 46 nM, respectively. 

Chemical Structure

52617 - A-674563 | CAS 552325-73-2

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