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4EGI-1

Catalog No.: 102608
Cas No.: 315706-13-9
Purity : 98% 
102608 - 4EGI-1 | CAS 315706-13-9

Catalog number : 102608

CAS number : 315706-13-9

Molecular Formula : C18H16Cl2N4O4S 

Molecular Weight : 455.315 

Iupac Chemical Name : 2-[[4-(3,4-dichlorophenyl)-1,3-thiazol-2-yl]hydrazinylidene]-3-(2-nitrophenyl)propanoic acid 

Smile : C1=CC=C(C(=C1)CC(=NNC2=NC(=CS2)C3=CC(=C(C=C3)Cl)Cl)C(=O)O)[N+](=O)[O-]

InChiKey : KFRKRECSIYXARE-UHFFFAOYSA-N

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SynonymseIF4E/eIF4G Interaction Inhibitor 
Molecular FormulaC18H16Cl2N4O4S 
Molecular Weight455.315 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileC1=CC=C(C(=C1)CC(=NNC2=NC(=CS2)C3=CC(=C(C=C3)Cl)Cl)C(=O)O)[N+](=O)[O-]
InChiKeyKFRKRECSIYXARE-UHFFFAOYSA-N
InChiInChI=1S/C18H12Cl2N4O4S/c19-12-6-5-10(7-13(12)20)15-9-29-18(21-15)23-22-14(17(25)26)8-11-3-1-2-4-16(11)24(27)28/h1-7,9H,8H2,(H,21,23)(H,25,26)
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4EGI-1 is a cell-permeable hydrazone compound that reversibly binds eukaryotic translation initiation factor 4E (eIF4E; KD = 25 M) and disrupts eIF4E/eIF4G, but not eIF4E/4E-BP1, complex formation.
 

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