(+)-MK-801 is an uncompetitive antagonist of the N-Methyl-D-aspartate (NMDA) receptor, a glutamate receptor discovered by a team at Merck in 1982. (+)-MK-801 has been shown to bind to and inhibit the serotonin and dopamine transporters as well.
For research use only. We do not sell to patients.
| Name | (+)-MK801(maleate) |
|---|---|
| Iupac Chemical Name | (5S,10R)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5,10-imine maleate |
| Synonyms | Dizocilpine maleate, Dizocilpine |
| Molecular Formula | C16H15N.C4H4O4 |
| Molecular Weight | 337.37 |
| Smile | C[C@]12c3ccccc3C[C@H](N1)c4c2cccc4.C(=C\C(=O)O)\C(=O)O |
| InChiKey | QLTXKCWMEZIHBJ-FWHYOZOBSA-N |
| InChi | InChI=1S/C16H15N.C4H4O4/c1-16-13-8-4-2-6-11(13)10-15(17-16)12-7-3-5-9-14(12)16;5-3(6)1-2-4(7)8/h2-9,15,17H,10H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t15-,16+;/m0./s1 |
| CAS Number | 77086-22-7 |
| MDL | MFCD00082466 |
| Related CAS |
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% by HPLC |
| Storage | 3 years -20ºCpowder 6 months-80ºCin solvent |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
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| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |