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Inhibitors & Agonists

161009016XL3881251156-08-798% by HPLC 
XL388 inhibited cellular phosphorylation of mTOR complex 1 (p-p70S6K, pS6, and p-4E-B
161009017Chrysophanic acid481-74-398% by HPLC 
Chrysophanic acid preferentially blocked proliferation in SNU-C5 cells but not in oth
161009018Zotarolimus221877-54-998% by HPLC 
It is a semi-synthetic derivative of rapamycin. It was designed for use in stents wit
611804Akt1 and Akt2-IN-1893422-47-498% 
Akt1 and Akt2-IN-1 is an allosteric inhibitor of Akt1 (IC50 = 3.5 nM) and Akt2 (IC50
LY3023414 is an oral ATP competitive inhibitor of the class I PI3K isoforms, mTOR and
611815CC-115 hydrochloride1300118-55-198% 
CC-115 hydrochloride is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM). CC-115 shows go
611901ON 1460401404231-34-098% 
ON 146040 is the first dual PI3K and BCR-ABL inhibitor that targets the STAT3 and STA
TGR-1202 is an orally available, next generation PI3Kdelta inhibitor, inhibits PI3K a
PI4KIII-IN-9 is a potent PI4KIII inhibitor (IC50 of 7 nM) and is >140-fold selecti
Deguelin, a natural product isolated from plants in the Mundulea sericea family, is a
GSK2292767 is a potent and selective PI3K inhibitor.GSK2292767 is highly selective fo
ETC-1002,also known as Bempedoic acid, is an orally available, once-daily LDL-C lower