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Inhibitors & Agonists

CATALOG NOPRODUCT NAMECASPURITYSTRUCTURE
122925AZD81861627494-13-698% 
AZD8186 is an isoform-specific small-molecule PI3K inhibitor, potently inhibits PI3K
12309CUDC-9071339928-25-498% 
CUDC-907 potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes.
123014BGT-226 free base915020-55-298% 
BGT226 is a phosphatidylinositol 3-kinase (PI3K) inhibitor with potential antineoplas
123018Ridaforolimus572924-54-098% 
Ridaforolimus is a selective mTOR inhibitor with IC50 of 0.2 nM; while not classified
123019AZD-80551009298-09-298% 
AZD-8055 is an inhibitor of the mammalian target of rapamycin (mTOR) with potential a
123020PF-046915021013101-36-498% 
PF-04691502 is an ATP-competitive PI3K(///)/mTOR dual inhibitor with Ki of 1.8 nM/2.1
011121INK-1281224844-38-598% 
INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less
012004CC-1151228013-15-798% 
CC-115 is a dual inhibitor of DNA-dependent protein kinase and mammalian target of ra
012009Tenalisib1639417-53-0 or 1693773-94-298% 
Tenalisib is a potent and selective dual PI3K/ inhibitor that inhibited growth of B-c
021802CC-2231228013-30-698% 
CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity
16062804PIK-293900185-01-598% by HPLC 
PIK-293 is a PI3K inhibitor
16071405GDC-00841382979-44-398% by HPLC 
GDC-0084, also known as RG7666, is a phosphatidylinositol 3-kinase (PI3K) inhibitor w