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Inhibitors & Agonists

CZC24832 is a selective inhibitor of PI 3-kinase (IC50 = 1.0 M in a PI 3-K-dependent
pexidartinib is acapsule formulation containing a small-molecule receptor tyrosine ki
52820Torin 11222998-36-898% 
Torin 1 is a potent inhibitor of mTORC1/2 with IC50 of 2 nM/10 nM; exhibits 1000-fold
62503Apitolisib(GDC-0980,RG7422)1032754-93-0>98% by HPLC 
Apitolisib(GDC-0980,RG7422) is a dual PI3K/mTOR inhibitor.GDC-0980 was potent across
62504Alpelisib(BYL719)1217486-61-7>98% by HPLC 
NVP-BYL719 is novel and specific PI3K inhibitor.NVP-BYL719 has displayed promising re
62702GDC-03491207360-89-1>98% by HPLC 
GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR.
71804AZD2014(Vistusertib)1009298-59-298% by HPLC 
1) Sponsor:AstraZeneca 2) Phase:Phase II 3) AZD2014 is a potent (IC50 2.81 nM), sel
PKI-587 is a potent inhibitor to PI3K-, PI3K-, and mTOR (FRAP) with IC50 of 0.4 nM, 5
90732Taselisib(GDC-0032)1282512-48-498% by HPLC 
GDC-0032 (RG7604) is a small molecule PI3 kinase inhibitor. PI3 Kinase is an oncogene
Fruquintinib is an orally available, small molecule inhibitor of vascular endothelial
100502Pluripotin(SC-1)839707-37-898% by HPLC 
SC1 (Pluripotin) was identified in a cell-based chemical library screen for small mol
Temsirolimus is a recently developed mTOR inhibitor. with improved aqueous solubility