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Veliparib (ABT-888)

Catalog No.: 51610
Cas No.: 912444-00-9
Purity : 98% 
51610 - Veliparib (ABT-888) | CAS 912444-00-9

Catalog number : 51610

CAS number : 912444-00-9

分子式 : C13H16N4O 

分子量 : 244.29 

Iupac 化学名称 : (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide 

Smile : C[C@]1(NCCC1)C1=NC2=C(N1)C=CC=C2C(=O)N

InChiKey : JNAHVYVRKWKWKQ-CYBMUJFWSA-N

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同义词ABT-888; ABT 888; ABT888 
英文同义词ABT-888; ABT 888; ABT888 
分子式C13H16N4O 
分子量244.29 
外观off-white solid 
纯度98% 
可溶性5mg/ml in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature 
SmileC[C@]1(NCCC1)C1=NC2=C(N1)C=CC=C2C(=O)N
InChiKeyJNAHVYVRKWKWKQ-CYBMUJFWSA-N
InChiInChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1
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Veliparib (ABT-888) is a potent inhibitor of PARP1 and PARP2 with Ki of 5.2 nM and 2.9 nM, respectively. It is inactive to SIRT2. Phase 3. 

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