+86-27-65522453 sales@sun-shinechem.com

TAK-580 (MLN2480)

Catalog No.: 16062203
Cas No.: 1096708-71-2
Purity : 98% by HPLC 
16062203 - TAK-580 (MLN2480) | CAS 1096708-71-2

Catalog number : 16062203

CAS number : 1096708-71-2

分子式 : C17H12Cl2F3N7O2S 

分子量 : 506.29 

Iupac 化学名称 : (R)-2-(1-(6-amino-5-chloropyrimidine-4-carboxamido)ethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide 

Smile : NC1=C(C(=NC=N1)C(=O)N[C@H](C)C=1SC(=CN1)C(=O)NC1=NC=C(C(=C1)C(F)(F)F)Cl)Cl

InChiKey : VWMJHAFYPMOMGF-ZCFIWIBFSA-N

PackagingPriceAvailabilityPurityEstimated Shipping Time
BulkEnquiryEnquiry
Request Bulk Quote Download MSDS电话:+86-27-65522453 | Email:sales@sun-shinechem.com
同义词TAK580; MLN 2480 
英文同义词TAK580; MLN 2480 
分子式C17H12Cl2F3N7O2S 
分子量506.29 
外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileNC1=C(C(=NC=N1)C(=O)N[C@H](C)C=1SC(=CN1)C(=O)NC1=NC=C(C(=C1)C(F)(F)F)Cl)Cl
InChiKeyVWMJHAFYPMOMGF-ZCFIWIBFSA-N
InChiInChI=1S/C17H12Cl2F3N7O2S/c1-6(28-15(31)12-11(19)13(23)27-5-26-12)16-25-4-9(32-16)14(30)29-10-2-7(17(20,21)22)8(18)3-24-10/h2-6H,1H3,(H,28,31)(H2,23,26,27)(H,24,29,30)/t6-/m1/s1
Coming soon.
TAK-580, also known as MLN2480, BIIB024, and AMG 2112819, is an oral, selective pan-Raf kinase inhibitor. The Raf kinases (A-Raf, B-Raf and C-Raf) are key regulators of cell proliferation and survival within the mitogen-activated protein kinase (MAPK) pathway. The MAPK pathway is frequently disregulated in human cancers, often via activating mutations of Ras or Raf. 

1096708-71-2 - Request Bulk Quote

×
1096708-71-2 - Request Bulk Quote
Change