武汉永璨生物科技有限公司
+86-17702719238 sales@sun-shinechem.com

TAK-580 (MLN2480)

编号: 16062203
Cas号: 1096708-71-2
纯度: 98% by HPLC 

TAK-580, also known as MLN2480, BIIB024, and AMG 2112819, is an oral, selective pan-Raf kinase inhibitor. The Raf kinases (A-Raf, B-Raf and C-Raf) are key regulators of cell proliferation and survival within the mitogen-activated protein kinase (MAPK) pathway. The MAPK pathway is frequently disregulated in human cancers, often via activating mutations of Ras or Raf. 

仅供研究使用。 我们不向患者出售。

化学信息

名称TAK-580 (MLN2480)
Iupac 化学名称(R)-2-(1-(6-amino-5-chloropyrimidine-4-carboxamido)ethyl)-N-(5-chloro-4-(trifluoromethyl)pyridin-2-yl)thiazole-5-carboxamide 
同义词TAK580; MLN 2480 
英文同义词TAK580; MLN 2480 
分子式C17H12Cl2F3N7O2S 
分子量506.29 
SmileNC1=C(C(=NC=N1)C(=O)N[C@H](C)C=1SC(=CN1)C(=O)NC1=NC=C(C(=C1)C(F)(F)F)Cl)Cl
InChiKeyVWMJHAFYPMOMGF-ZCFIWIBFSA-N
InChiInChI=1S/C17H12Cl2F3N7O2S/c1-6(28-15(31)12-11(19)13(23)27-5-26-12)16-25-4-9(32-16)14(30)29-10-2-7(17(20,21)22)8(18)3-24-10/h2-6H,1H3,(H,28,31)(H2,23,26,27)(H,24,29,30)/t6-/m1/s1
Cas号1096708-71-2
相关CAS号

订购信息

包装价格库存纯度备货期
大货询价询价询价
Request Bulk Quote Download MSDS 电话 : +86-177 0271 9238   Email : sales@sun-shinechem.com
外观性状Solid powder 
纯度98% by HPLC 
存储-20 ºC for 3 years 
可溶性Soluble in DMSO 
处理方式
运输条件Shipped under ambient temperature 
海关编码
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

化学结构

16062203 - TAK-580 (MLN2480) | CAS 1096708-71-2

快速订购

Change