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R788 (Fostamatinib) Disodium

Catalog No.: 51609
Cas No.: 1025687-58-4
Purity : 98% 
51609 - R788 (Fostamatinib) Disodium | CAS 1025687-58-4

Catalog number : 51609

CAS number : 1025687-58-4

分子式 : C23H24FN6O9P.2Na 

分子量 : 624.42 

Iupac 化学名称 : 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-, sodium salt (1:2) 

Smile : CC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)([O-])[O-])C.[Na+].[Na+]

InChiKey : HSYBQXDGYCYSGA-UHFFFAOYSA-L

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同义词N/A 
英文同义词N/A 
分子式C23H24FN6O9P.2Na 
分子量624.42 
纯度98% 
存储3 years -20ºCpowder 6 months-80ºCin solvent 
SmileCC1(C(=O)N(c2c(ccc(n2)Nc3c(cnc(n3)Nc4cc(c(c(c4)OC)OC)OC)F)O1)COP(=O)([O-])[O-])C.[Na+].[Na+]
InChiKeyHSYBQXDGYCYSGA-UHFFFAOYSA-L
InChiInChI=1S/C23H26FN6O9P.2Na/c1-23(2)21(31)30(11-38-40(32,33)34)20-14(39-23)6-7-17(28-20)27-19-13(24)10-25-22(29-19)26-12-8-15(35-3)18(37-5)16(9-12)36-4;;/h6-10H,11H2,1-5H3,(H2,32,33,34)(H2,25,26,27,28,29);;/q;2*+1/p-2
MDLMFCD15146370
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R788 (Fostamatinib) disodium, a prodrug of the active metabolite R406, is a Syk inhibitor with IC50 of 41 nM, strongly inhibits Syk but not Lyn, 5-fold less potent to Flt3. Phase 3. 

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