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PF-06700841甲苯磺酸盐

Catalog No.: 19184
Cas No.: 1883299-62-4
Purity : >98%
19184 - PF-06700841甲苯磺酸盐 | CAS 1883299-62-4

Catalog number : 19184

CAS number : 1883299-62-4

分子式 : C25H29F2N7O4S

分子量 : 561.6088

Iupac 化学名称 : ((S)-2,2-difluorocyclopropyl)(3-(2-((1-methyl-1H-pyrazol-4-yl)amino)pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octan-8-yl)methanone 4-methylbenzenesulfonate

Smile : O=C([C@H]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3.OS(=O)(C6=CC=C(C)C=C6)=O

InChiKey : FAKGOYNHHHOTEN-WTMFEIAXSA-N

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同义词PF-06700841; PF 06700841; PF06700841; PF-6700841; PF 6700841; PF6700841; PF-06700841 tosylate salt;
英文同义词PF-06700841; PF 06700841; PF06700841; PF-6700841; PF 6700841; PF6700841; PF-06700841 tosylate salt;
分子式C25H29F2N7O4S
分子量561.6088
外观类白色至白色固体
纯度>98%
可溶性可溶于DMSO
存储短期可在0-4度保存,数天至数月;长期可在-20度保存三年。
运输条件可在常温下运输
SmileO=C([C@H]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3.OS(=O)(C6=CC=C(C)C=C6)=O
InChiKeyFAKGOYNHHHOTEN-WTMFEIAXSA-N
InChiInChI=1S/C18H21F2N7O.C7H8O3S/c1-25-8-11(7-22-25)23-17-21-5-4-15(24-17)26-9-12-2-3-13(10-26)27(12)16(28)14-6-18(14,19)20;1-6-2-4-7(5-3-6)11(8,9)10/h4-5,7-8,12-14H,2-3,6,9-10H2,1H3,(H,21,23,24);2-5H,1H3,(H,8,9,10)/t12?,13?,14-;/m0./s1
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PF-06700841是JAK1和TYK2激酶的抑制剂。PF-06700841甲磺酸盐可能是一种治疗系统性红斑狼疮和斑块型银屑病的药物。

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