Montelukast sodium
编号: 52809
Cas号: 151767-02-1
纯度: 98%
Montelukast Sodium(Singulair) is a potent, selective, anti-inflammatory CysLT1 receptor antagonist (IC50 < 5nM) with no appreciable affect on the CysLT2 receptor. In rat colitis Montelukast Sodium (Singulair) has demonstrated the ability to increase PGE2 production and lower COX-2 expression. Inhibition is competitive with respect to leukotrienes - particularly LTD4, a biologically active mediator that plays an important role in the control of several biochemical pathways involving pulmonary and immune system function.
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化学信息
| 名称 | Montelukast sodium |
|---|---|
| 分子式 | C35H35ClNNaO3S |
| 分子量 | 608.17 |
| Smile | CC(C)(c1ccccc1CC[C@H](c2cccc(c2)/C=C/c3ccc4ccc(cc4n3)Cl)SCC5(CC5)CC(=O)[O-])O.[Na+] |
| InChiKey | LBFBRXGCXUHRJY-HKHDRNBDSA-M |
| InChi | InChI=1S/C35H36ClNO3S.Na/c1-34(2,40)30-9-4-3-7-25(30)13-17-32(41-23-35(18-19-35)22-33(38)39)27-8-5-6-24(20-27)10-15-29-16-12-26-11-14-28(36)21-31(26)37-29;/h3-12,14-16,20-21,32,40H,13,17-19,22-23H2,1-2H3,(H,38,39);/q;+1/p-1/b15-10+;/t32-;/m1./s1 |
| Cas号 | 151767-02-1 |
| MDL | MFCD00931431 |
| 相关CAS号 |
订购信息
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