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Ansamitocin P-3 编号 : 16122857

化学信息

产品英文名称Ansamitocin P-3
Iupac 化学名称Ansamitocin P-3 
同义词NSC292222; NSC 292222; NSC-292222; Ansamitocin P-3; Maytansinol isobutyrate 
英文同义词NSC292222; NSC 292222; NSC-292222; Ansamitocin P-3; Maytansinol isobutyrate 
分子式C32H43ClN2O9 
分子量635.15 
SmileC[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/Cc3cc(c(c(c3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@@H]1O4)C)OC(=O)C(C)C)C)\C)OC)(NC(=O)O2)O
InChiKeyOPQNCARIZFLNLF-KUDLRRJMSA-N
InChiInChI=1S/C32H43ClN2O9/c1-17(2)29(37)43-25-15-26(36)35(6)21-13-20(14-22(40-7)27(21)33)12-18(3)10-9-11-24(41-8)32(39)16-23(42-30(38)34-32)19(4)28-31(25,5)44-28/h9-11,13-14,17,19,23-25,28,39H,12,15-16H2,1-8H3,(H,34,38)/b11-9+,18-10+/t19-,23+,24-,25+,28-,31+,32+/m1/s1
Cas66547-09-9
MDLMFCD00274586

技术数据

外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
质量控制

产品详情

Ansamitocin P-3 (AP-3) is an active and potent anti-tumor maytansinoid, which is usually produced by Actinosynnema spp. Ansamitocin P-3 showed potent cytotoxicity against the human solid tumor cell lines A-549, HT-29. Ansamitocin P-3 is a useful material to make anticancer drug mertansine and emtansine. 

结构

16122857 - Ansamitocin P-3 | CAS 66547-09-9

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