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AMG 900

Catalog No.: 011803
Cas No.: 945595-80-2
Purity : 98% 
011803 - AMG 900 | CAS 945595-80-2

Catalog number : 011803

CAS number : 945595-80-2

分子式 : C28H21N7OS 

分子量 : 503.578 

Iupac 化学名称 : N-[4-[3-(2-aminopyrimidin-4-yl)pyridin-2-yl]oxyphenyl]-4-(4-methylthiophen-2-yl)phthalazin-1-amine 

Smile : CC1=CSC(=C1)C2=NN=C(C3=CC=CC=C32)NC4=CC=C(C=C4)OC5=C(C=CC=N5)C6=NC(=NC=C6)N

InChiKey : IVUGFMLRJOCGAS-UHFFFAOYSA-N

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同义词AMG-900; AMG900 
英文同义词AMG-900; AMG900 
分子式C28H21N7OS 
分子量503.578 
外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
SmileCC1=CSC(=C1)C2=NN=C(C3=CC=CC=C32)NC4=CC=C(C=C4)OC5=C(C=CC=N5)C6=NC(=NC=C6)N
InChiKeyIVUGFMLRJOCGAS-UHFFFAOYSA-N
InChiInChI=1S/C28H21N7OS/c1-17-15-24(37-16-17)25-20-5-2-3-6-21(20)26(35-34-25)32-18-8-10-19(11-9-18)36-27-22(7-4-13-30-27)23-12-14-31-28(29)33-23/h2-16H,1H3,(H,32,35)(H2,29,31,33)
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AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM; >10-fold selective for Aurora kinases than p38, Tyk2, JNK2, Met and Tie2. 

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