ZLN024 hydrochloride
Catalog No: 611814
CAS Number:
Purity: 98%
ZLN024 Hcl is a novel AMPK allosteric activator; activated 111 and 211 by around 2C2.5 fold with an EC50 of about 1C2 uM.
ZLN024 activated AMPK in L6 myotubes and stimulated glucose uptake and fatty acid oxidation without increasing the ADP/ATP ratio. ZLN024 also activated AMPK in primary hepatocytes, decreased fatty acid synthesis and glucose output. Treatment of db/db mice with 15 mg/kg/day ZLN024 improved glucose tolerance; liver tissue weight, triacylglycerol and the total cholesterol content were decreased. The hepatic transcriptional level of G6Pase, FAS and mtGPAT were reduced.
For research use only. We do not sell to patients.
Chemical Information
| Name | ZLN024 hydrochloride |
|---|---|
| Iupac Chemical Name | ZLN024 hydrochloride |
| Synonyms | ZLN-024 hydrochloride |
| Molecular Formula | C13H14BrClN2OS |
| Molecular Weight | 361.69 |
| Smile | C[Si](C)(C)CSCCl |
| InChiKey | IKWIERSJEROYFH-UHFFFAOYSA-N |
| InChi | InChI=1S/C5H13ClSSi/c1-8(2,3)5-7-4-6/h4-5H2,1-3H3 |
| CAS Number | |
| MDL | MFCD17013410 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
