Turofexorate isopropyl
Catalog No: 17030707
CAS Number: 629664-81-9
Purity: 98%
Turofexorate isopropyl, also known as WAY-362450 and XL335, is a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR) (EC(50) = 4 nM, Eff = 149%), which attenuates liver inflammation and fibrosis in murine model of non-alcoholic steatohepatitis.
For research use only. We do not sell to patients.
Chemical Information
| Name | Turofexorate isopropyl |
|---|---|
| Iupac Chemical Name | Isopropyl 3-(3,4-difluorobenzoyl)-1,1-dimethyl-1,2,3,6-tetrahydroazepino(4,5-b)indole-5- carboxylate |
| Synonyms | WAY-362450; WAY362450; WAY 362450; XL335; XL 335; XL-335; Turofexorate isopropyl |
| Molecular Formula | C25H24F2N2O3 |
| Molecular Weight | 438.4748 |
| Smile | FC=1C=C(C(=O)N2C=C(C=3NC=4C=CC=CC4C3C(C2)(C)C)C(=O)OC(C)C)C=CC1F |
| InChiKey | INASOKQDNHHMRE-UHFFFAOYSA-N |
| InChi | InChI=1S/C25H24F2N2O3/c1-14(2)32-24(31)17-12-29(23(30)15-9-10-18(26)19(27)11-15)13-25(3,4)21-16-7-5-6-8-20(16)28-22(17)21/h5-12,14,28H,13H2,1-4H3 |
| CAS Number | 629664-81-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
