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TRV130 ( Oliceridine )

Catalog No.: 1781701
Cas No.: 1401031-39-7
Purity : 98% Min.

TRV 130 Hcl is a novel -opioid receptor (MOR) G protein-biased ligand; elicits robust G protein signaling ( pEC50=8.1), with potency and efficacy similar to morphine, but with far less -arrestin recruitment and receptor internalization. 

For research use only. We do not sell to patients.

Chemical Information

NameTRV130 ( Oliceridine )
Iupac Chemical Name(R)-N-((3-methoxythiophen-2-yl)methyl)-2-(9-(pyridin-2-yl)-6-oxaspiro[4.5]decan-9-yl)ethanamine hydrochloride
SynonymsTRV-130 ;TRV130 ;TRV 130 ;Oliceridine 
Molecular Formula423.01
Molecular WeightC22H31ClN2O2S
SmileCOC1=C(CNCC[C@@](C2)(C3=NC=CC=C3)CCOC42CCCC4)SC=C1.[H]Cl
InChiKeyYIIWXYLJZRISQP-ZMBIFBSDSA-N
InChiInChI=1S/C22H30N2O2S.ClH/c1-25-18-7-15-27-19(18)16-23-13-10-21(20-6-2-5-12-24-20)11-14-26-22(17-21)8-3-4-9-22;/h2,5-7,12,15,23H,3-4,8-11,13-14,16-17H2,1H3;1H/t21-;/m1./s1
CAS Number1401031-39-7
Related CAS1401031-39-7 (HCl) 1401028-24-7 (free base)

Ordering Information

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Formulationwhite solid 
Purity98% Min.
Storage3 years -20ºCpowder 
Solubility5mg/ml in DMSO 
Handling
Shipping ConditionShipped under ambient temperature. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

1781701 - TRV130 ( Oliceridine ) | CAS 1401031-39-7

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