Sacubitril sodium
Catalog No: 17030108
CAS Number: 149690-05-1
Purity: 98%
Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume.
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Chemical Information
| Name | Sacubitril sodium |
|---|---|
| Iupac Chemical Name | Sacubitril sodium |
| Synonyms | Sacubitril sodium; AHU377; AHU 377; AHU-377; LCZ696 |
| Molecular Formula | C24H28NNaO5 |
| Molecular Weight | 433.4798 |
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| InChi | |
| CAS Number | 149690-05-1 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
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| Mechanism | |
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| Clinical study |
Not available
Chemical Structure
