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SNS-314 Mesylate

Catalog No: 52102
CAS Number: 1057249-41-8
Purity: 98% 

SNS-314 Mesylate is a potent and selective inhibitor of Aurora AAurora B and Aurora C with IC50 of 9 nM, 31 nM, and 3 nM, respectively. It is less potent to Trk A/B, Flt4, Fms, Axl, c-Raf and DDR2. Phase 1. 

For research use only. We do not sell to patients.

Chemical Information

NameSNS-314 Mesylate
Iupac Chemical Name1-(3-chlorophenyl)-3-(5-(2-(thieno[3,2-d]pyrimidin-4-ylamino)ethyl)thiazol-2-yl)urea methanesulfonate 
SynonymsN/A 
Molecular FormulaC18H15ClN6OS2.CH4O3S 
Molecular Weight527.04 
SmileCS(=O)(=O)O.ClC=1C=C(C=CC1)NC(=O)NC=1SC(=CN1)CCNC=1C2=C(N=CN1)C=CS2
InChiKeyFYCODPVDEFFWSR-UHFFFAOYSA-N
InChiInChI=1S/C18H15ClN6OS2.CH4O3S/c19-11-2-1-3-12(8-11)24-17(26)25-18-21-9-13(28-18)4-6-20-16-15-14(5-7-27-15)22-10-23-16;1-5(2,3)4/h1-3,5,7-10H,4,6H2,(H,20,22,23)(H2,21,24,25,26);1H3,(H,2,3,4)
CAS Number1057249-41-8
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Ordering Information

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Purity98% 
Storage3 years -20ºCpowder 
Solubility5mg/ml in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
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Targets
Mechanism
Cell study
Animal study
Clinical study
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Chemical Structure

52102 - SNS-314 Mesylate | CAS 1057249-41-8

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