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SB-743921 HCl

Catalog No: 17011609
CAS Number: 940929-33-9
Purity: 98% 

SB-743921 is a synthetic small molecule with potential antineoplastic properties. SB-743921 selectively inhibits kinesin spindle protein (KSP), an important protein involved in the early stages of mitosis that is expressed in proliferating cells. Inhibition of KSP results in inhibition of mitotic spindle assembly and interrupts cell division, thereby causing cell cycle arrest and induction of apoptosis. 

For research use only. We do not sell to patients.

Chemical Information

NameSB-743921 HCl
Iupac Chemical Name(S)-N-(3-aminopropyl)-N-(1-(3-benzyl-7-chloro-4-oxo-4H-chromen-2-yl)-2-methylpropyl)-4-methylbenzamide hydrochloride 
SynonymsSB743921; SB 743921; SB743921 
Molecular FormulaC31H34Cl2N2O3 
Molecular Weight553.52 
SmileCl.NCCCN(C(C1=CC=C(C=C1)C)=O)[C@@H](C(C)C)C=1OC2=CC(=CC=C2C(C1CC1=CC=CC=C1)=O)Cl
InChiKeyMLMZVWABFOLFGV-JCOPYZAKSA-N
InChiInChI=1S/C31H33ClN2O3.ClH/c1-20(2)28(34(17-7-16-33)31(36)23-12-10-21(3)11-13-23)30-26(18-22-8-5-4-6-9-22)29(35)25-15-14-24(32)19-27(25)37-30;/h4-6,8-15,19-20,28H,7,16-18,33H2,1-3H3;1H/t28-;/m0./s1
CAS Number940929-33-9
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Ordering Information

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Formulationcrystalline solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

17011609 - SB-743921 HCl | CAS 940929-33-9

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