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SB 525334

Catalog No: 102205
CAS Number: 356559-20-1
Purity: 98% 

SB 525334 is a potent and selective inhibitor of TGF_beta_ receptor I (ALK5) with IC50 of 14.3 nM, is 4-fold less potent to ALK4 than ALK5 and inactive to ALK2, 3, and 6. 

For research use only. We do not sell to patients.

Chemical Information

NameSB 525334
Iupac Chemical Name6-[2-tert-butyl-5-(6-methylpyridin-2-yl)-1H-imidazol-4-yl]quinoxaline 
SynonymsSB-525334; SB525334 
Molecular FormulaC21H21N5 
Molecular Weight343.42 
SmileC(C)(C)(C)C=1NC(=C(N1)C=1C=C2N=CC=NC2=CC1)C1=NC(=CC=C1)C
InChiKeyDKPQHFZUICCZHF-UHFFFAOYSA-N
InChiInChI=1S/C21H21N5/c1-13-6-5-7-16(24-13)19-18(25-20(26-19)21(2,3)4)14-8-9-15-17(12-14)23-11-10-22-15/h5-12H,1-4H3,(H,25,26)
CAS Number356559-20-1
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

102205 - SB 525334 | CAS 356559-20-1

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