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Melphalan flufenamide

Catalog No: 192279
CAS Number: 380449-51-4
Purity: >98%

Melphalan flufenamide, also known as Melflufen, J-1, or Prodrug J-1, is a melphalan prodrug in which the alkylating agent melphalan is bound to flufenamide, with potential antineoplastic and anti-angiogenic activities.

For research use only. We do not sell to patients.

Chemical Information

NameMelphalan flufenamide
Iupac Chemical Nameethyl (S)-2-((S)-2-amino-3-(4-(bis(2-chloroethyl)amino)phenyl)propanamido)-3-(4-fluorophenyl)propanoate
SynonymsJ-1; J1; J 1; Prodrug J-1, Melflufen, Melphalan flufenamide
Molecular FormulaC24H30Cl2FN3O3
Molecular Weight498.4204
SmileO=C(OCC)[C@H](CC1=CC=C(F)C=C1)NC([C@H](CC2=CC=C(N(CCCl)CCCl)C=C2)N)=O
InChiKeyYQZNKYXGZSVEHI-VXKWHMMOSA-N
InChiInChI=1S/C24H30Cl2FN3O3/c1-2-33-24(32)22(16-18-3-7-19(27)8-4-18)29-23(31)21(28)15-17-5-9-20(10-6-17)30(13-11-25)14-12-26/h3-10,21-22H,2,11-16,28H2,1H3,(H,29,31)/t21-,22-/m0/s1
CAS Number380449-51-4
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Ordering Information

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FormulationOff-white solid to white solid
Purity>98%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
Handling
Shipping ConditionShipped under ambient temperature
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

192279 - Melphalan flufenamide  | CAS 380449-51-4

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