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Mavoglurant

Catalog No: 17030612
CAS Number: 543906-09-8
Purity: 98% 

Mavoglurant, aslo known as AFQ056, is an experimental drug candidate for the treatment of fragile X syndrome. Mavoglurant exerts its effect as an antagonist of the metabotropic glutamate receptor 5 (mGLU5). Novartis discontinued development of mavoglurant for fragile X syndrome in April 2014 following disappointing trial results. Currently Novartis is conducting a clinical trial with this drug on obsessive compulsive disorder. 

For research use only. We do not sell to patients.

Chemical Information

NameMavoglurant
Iupac Chemical Namemethyl (3aR,4S,7aR)-4-hydroxy-4-(m-tolylethynyl)octahydro-1H-indole-1-carboxylate 
SynonymsAFQ056; AFQ-056; AFQ 056; Mavoglurant 
Molecular FormulaC19H23NO3 
Molecular Weight313.397 
SmileO[C@@]1([C@@H]2CCN([C@@H]2CCC1)C(=O)OC)C#CC=1C=C(C=CC1)C
InChiKeyZFPZEYHRWGMJCV-ZHALLVOQSA-N
InChiInChI=1S/C19H23NO3/c1-14-5-3-6-15(13-14)8-11-19(22)10-4-7-17-16(19)9-12-20(17)18(21)23-2/h3,5-6,13,16-17,22H,4,7,9-10,12H2,1-2H3/t16-,17-,19-/m1/s1
CAS Number543906-09-8
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Ordering Information

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Formulationoff-white solid 
Purity98% 
Storage3 years -20ºCpowder 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

17030612 - Mavoglurant | CAS 543906-09-8

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