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MDL 28170

Catalog No: 102610
CAS Number: 88191-84-8
Purity: 98% 

MDL 28170 is a potent, cell-permeable, and selective inhibitor of calpain and cathepsin B (Ki values are 10 and 25 nM respectively), which does not inhibit trypsin-like serine proteases. Rapidly penetrates the blood-brain barrier following systemic administration and displays neuroprotective effects in vivo.
 

For research use only. We do not sell to patients.

Chemical Information

NameMDL 28170
Iupac Chemical NameN-benzyloxycarbonyl-(S)-valinylphenylalaninal 
SynonymsZ-Val-Phe-CHO; Carbobenzoxy-valinyl-phenylalaninal; Calpain Inhibitor III 
Molecular FormulaC₂₂H₂₆N₂O₄ 
Molecular Weight382.45 
SmileCC(C)C(C(=O)NC(CC1=CC=CC=C1)C=O)NC(=O)OCC2=CC=CC=C2
InChiKeyNGBKFLTYGSREKK-UHFFFAOYSA-N
InChiInChI=1S/C22H26N2O4/c1-16(2)20(24-22(27)28-15-18-11-7-4-8-12-18)21(26)23-19(14-25)13-17-9-5-3-6-10-17/h3-12,14,16,19-20H,13,15H2,1-2H3,(H,23,26)(H,24,27)
CAS Number88191-84-8
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Ordering Information

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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

102610 - MDL 28170 | CAS 88191-84-8

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