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LY2835219(Abemaciclib)

Catalog No.: 51605
Cas No.: 1231930-82-7
Purity : 98% 

LY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM, respectively. Phase 3. 

For research use only. We do not sell to patients.

Chemical Information

NameLY2835219(Abemaciclib)
Iupac Chemical Name2-Pyrimidinamine, N-[5-[(4-ethyl-1-piperazinyl)methyl]-2-pyridinyl]-5-fluoro-4-[4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazol-6-yl]-, methanesulfonate (1:1) 
SynonymsLY-2835219,Bemaciclib 
Molecular FormulaC27H32F2N8.CH4O3S 
Molecular Weight602.7 
SmileCCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F.CS(=O)(=O)O
InChiKeyNCJPFQPEVDHJAZ-UHFFFAOYSA-N
InChiInChI=1S/C27H32F2N8.CH4O3S/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26;1-5(2,3)4/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34);1H3,(H,2,3,4)
CAS Number1231930-82-7
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Ordering Information

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Formulationlight yellow solid 
Purity98% 
Storage3 years -20ºCpowder 
Solubility5mg/ml in DMSO 
Handling
Shipping ConditionShipped under ambient temperature. 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

51605 - LY2835219(Abemaciclib) | CAS 1231930-82-7

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