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FL118

Catalog No.: 102621
Cas No.: 151636-76-9
Purity : 98% 
102621 - FL118 | CAS 151636-76-9

Catalog number : 102621

CAS number : 151636-76-9

Molecular Formula : C21H16N2O6 

Molecular Weight : 392.36 

Iupac Chemical Name : 7-ethyl-7-hydroxy-10H-1,3-Dioxolo(4,5-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-8,11(7H,12H)-dione 

Smile : CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=C6C(=CC5=C4)OCO6)O

InChiKey : RPFYDENHBPRCTN-UHFFFAOYSA-N

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SynonymsCID 72403; NSC 634724 
Molecular FormulaC21H16N2O6 
Molecular Weight392.36 
AppearanceSolid powder 
Purity98% 
SolubilitySoluble in DMSO 
Storage-20 ºC for 3 years 
Shipping ConditionShipped under ambient temperature 
SmileCCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=C6C(=CC5=C4)OCO6)O
InChiKeyRPFYDENHBPRCTN-UHFFFAOYSA-N
InChiInChI=1S/C21H16N2O6/c1-2-21(26)13-5-15-18-11(7-23(15)19(24)12(13)8-27-20(21)25)3-10-4-16-17(29-9-28-16)6-14(10)22-18/h3-6,26H,2,7-9H2,1H3
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FL118 is a novel camptothecin derivative, is insensitive to ABCG2 expression and shows improved efficacy in comparison with irinotecan in colon and lung cancer models with ABCG2-induced resistance. 

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