Etravirine (TMC125)
Catalog No: 16122767
CAS Number: 269055-15-4
Purity: 98%
Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.Etravirine (TMC125), is highly active against wild-type HIV-1 with EC50 of 1.4 nM to 4.8 nM and shows some activity against HIV-2 with EC50 of 3.5 M. TMC125 also inhibits a series of HIV-1 group M subtypes and circulating recombinant forms and a group O virus.
For research use only. We do not sell to patients.
Chemical Information
| Name | Etravirine (TMC125) |
|---|---|
| Iupac Chemical Name | Etravirine (TMC125) |
| Synonyms | R-165335 |
| Molecular Formula | C20H15BrN6O |
| Molecular Weight | 435.28 |
| Smile | Cc1cc(cc(c1Oc2c(c(nc(n2)Nc3ccc(cc3)C#N)N)Br)C)C#N |
| InChiKey | PYGWGZALEOIKDF-UHFFFAOYSA-N |
| InChi | InChI=1S/C20H15BrN6O/c1-11-7-14(10-23)8-12(2)17(11)28-19-16(21)18(24)26-20(27-19)25-15-5-3-13(9-22)4-6-15/h3-8H,1-2H3,(H3,24,25,26,27) |
| CAS Number | 269055-15-4 |
| MDL | MFCD09837879 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | crystalline solid |
|---|---|
| Purity | 98% |
| Storage | 3 years -20ºCpowder |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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