Etamicastat HCl salt
Catalog No: 16071009
CAS Number: 677773-32-9
Purity: 98% by HPLC
Etamicastat, also known as BIA 5-453, is a potent, reversible, peripherally selective dopamine -hydroxylase inhibitor (DBH inhibitor). Chronic dopamine ß-hydroxylase inhibition with etamicastat effectively decreases blood pressure, although does not prevent the development of hypertension in the spontaneously hypertensive rat.
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Chemical Information
| Name | Etamicastat HCl salt |
|---|---|
| Iupac Chemical Name | (R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydro-2H-imidazole-2-thione hydrochloride |
| Synonyms | BIA 5-453; BIA5-453 |
| Molecular Formula | C14H16ClF2N3OS |
| Molecular Weight | 347.8088 |
| Smile | Cl.NCCC1=CNC(N1[C@H]1COC2=C(C=C(C=C2C1)F)F)=S |
| InChiKey | CKRDOSZCFINPAD-RFVHGSKJSA-N |
| InChi | InChI=1S/C14H15F2N3OS.ClH/c15-9-3-8-4-11(7-20-13(8)12(16)5-9)19-10(1-2-17)6-18-14(19)21;/h3,5-6,11H,1-2,4,7,17H2,(H,18,21);1H/t11-;/m1./s1 |
| CAS Number | 677773-32-9 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Solid powder |
|---|---|
| Purity | 98% by HPLC |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
