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Erlotinib HCl (OSI-744)

Catalog No.: 51613
Cas No.: 183319-69-9
Purity : 98% 
51613 - Erlotinib HCl (OSI-744) | CAS 183319-69-9

Catalog number : 51613

CAS number : 183319-69-9

Molecular Formula : C22H23N3O4.HCl 

Molecular Weight : 429.90 

Iupac Chemical Name : N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine hydrochloride 

Smile : COCCOC1=CC2=NC=NC(NC3=CC=CC(C#C)=C3)=C2C=C1OCCOC.[H]Cl

InChiKey : GTTBEUCJPZQMDZ-UHFFFAOYSA-N

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SynonymsTarceva; CP-358774; OSI-774; NSC 718781 
Molecular FormulaC22H23N3O4.HCl 
Molecular Weight429.90 
Appearancecrystalline solid 
Purity98% 
SolubilityDMSO ��2.8mg/mL Water <1.2mg/mL Ethanol <1.2mg/mL 
Storage3 years -20ºCpowder 
Shipping ConditionShipped under ambient temperature as non-hazardous chemical. 
SmileCOCCOC1=CC2=NC=NC(NC3=CC=CC(C#C)=C3)=C2C=C1OCCOC.[H]Cl
InChiKeyGTTBEUCJPZQMDZ-UHFFFAOYSA-N
InChiInChI=1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H
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Erlotinib HCl (OSI-744) is an EGFR inhibitor with IC50 of 2 nM, >1000-fold more sensitive for EGFR than human c-Src or v-Abl. 

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