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Cilofexor ( GS-9674 )

Catalog No: 19132
CAS Number: 1418274-28-8
Purity: ≧98.0%

Cilofexor (also known as GS-9674) is a nonsteroidal farnesoid X receptor (FXR) agonist in clinical trials for the treatment of non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH),and primary sclerosing cholangitis (PSC).

For research use only. We do not sell to patients.

Chemical Information

NameCilofexor ( GS-9674 )
Iupac Chemical Name2-(3-(2-chloro-4-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4-yl)methoxy)phenyl)-3-hydroxyazetidin-1-yl)isonicotinic acid
SynonymsCilofexor; GS-9674; GS 9674; GS9674;
Molecular FormulaC28H22Cl3N3O5
Molecular Weight586.85
SmileOC(C1=CC=NC(N2CC(O)(C2)C3=C(C=C(C=C3)OCC4=C(ON=C4C5=C(C=CC=C5Cl)Cl)C6CC6)Cl)=C1)=O
InChiKeyKZSKGLFYQAYZCO-UHFFFAOYSA-N
InChiInChI=1S/C28H22Cl3N3O5/c29-20-2-1-3-21(30)24(20)25-18(26(39-33-25)15-4-5-15)12-38-17-6-7-19(22(31)11-17)28(37)13-34(14-28)23-10-16(27(35)36)8-9-32-23/h1-3,6-11,15,37H,4-5,12-14H2,(H,35,36)
CAS Number1418274-28-8
Related CAS1418274-28-8

Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationOff-white solid to white solid
Purity≧98.0%
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO
HandlingRefer to MSDS operation
Shipping ConditionShipped under ambient temperature
HS Code2934200090
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

19132 - Cilofexor ( GS-9674 ) | CAS 1418274-28-8

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