Abemaciclib ( LY2835219)
Catalog No: 178141
CAS Number: 1231929-97-7
Purity: 98.0%
Abemaciclib, also known as LY2835219, is orally available cyclin-dependent kinase (CDK) inhibitor that targets the CDK4 (cyclin D1) and CDK6 (cyclin D3) cell cycle pathway, with potential antineoplastic activity.
For research use only. We do not sell to patients.
Chemical Information
| Name | Abemaciclib ( LY2835219) |
|---|---|
| Iupac Chemical Name | N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-5-fluoro-4-(4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazol-6-yl)pyrimidin-2-amine |
| Synonyms | LY2835219; LY2835219; LY 2835219; Abemaciclib. |
| Molecular Formula | C27H32F2N8 |
| Molecular Weight | 506.59339 |
| Smile | C(C)N1CCN(CC1)CC=1C=CC(=NC1)NC1=NC=C(C(=N1)C=1C=C(C2=C(N(C(=N2)C)C(C)C)C1)F)F |
| InChiKey | UZWDCWONPYILKI-UHFFFAOYSA-N |
| InChi | InChI=1S/C27H32F2N8/c1-5-35-8-10-36(11-9-35)16-19-6-7-24(30-14-19)33-27-31-15-22(29)25(34-27)20-12-21(28)26-23(13-20)37(17(2)3)18(4)32-26/h6-7,12-15,17H,5,8-11,16H2,1-4H3,(H,30,31,33,34) |
| CAS Number | 1231929-97-7 |
| Related CAS |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | off-white solid |
|---|---|
| Purity | 98.0% |
| Storage | -20 ºC for 3 years |
| Solubility | Soluble in DMSO |
| Handling | |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
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