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ARRY-797 (ARRY-371797)

Catalog No: 191112
CAS Number: 1036404-17-7
Purity: 99% Min.

ARRY-797 is an oral, selective p38 mitogen-activated protein kinase inhibitor. ARRY-797 is being studied in a Phase 3 trial in patients with lamin A/C-related dilated cardiomyopathy (LMNA-related DCM), a rare, degenerative cardiovascular disease caused by mutations in the LMNA gene and characterized by poor prognosis.

According to reaxys, the correct CAS should be “1034189-82-6", please check the correct link.

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Chemical Information

NameARRY-797 (ARRY-371797)
Iupac Chemical Name5-(2,4-difluorophenoxy)-N-(2-(dimethylamino)ethyl)-1-isobutyl-1H -indazole-6-carboxamide
SynonymsARRY-797;ARRY 797;ARRY-371797;ARRY371797;
Molecular FormulaC22H26F2N4O2
Molecular Weight416.46
SmileO=C(C1=CC2=C(C=C1OC3=CC=C(F)C=C3F)C=NN2CC(C)C)NCCN(C)C
InChiKeyIFGWYHGYNVGVRB-UHFFFAOYSA-N
InChiInChI=1S/C22H26F2N4O2/c1-14(2)13-28-19-11-17(22(29)25-7-8-27(3)4)21(9-15(19)12-26-28)30-20-6-5-16(23)10-18(20)24/h5-6,9-12,14H,7-8,13H2,1-4H3,(H,25,29)
CAS Number1036404-17-7
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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Formulationoff-white solid 
Purity99% Min.
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
SolubilitySoluble in DMSO, not in water
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

191112 - ARRY-797 (ARRY-371797) | CAS 1036404-17-7

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