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ARRY-797 (ARRY-371797)

Catalog No.: 191112
Cas No.: 1036404-17-7
Purity : 99% Min.
191112 - ARRY-797 (ARRY-371797)  | CAS 1036404-17-7

Catalog number : 191112

CAS number : 1036404-17-7

Molecular Formula : C22H26F2N4O2

Molecular Weight : 416.46

Iupac Chemical Name : 5-(2,4-difluorophenoxy)-N-(2-(dimethylamino)ethyl)-1-isobutyl-1H -indazole-6-carboxamide

Smile : O=C(C1=CC2=C(C=C1OC3=CC=C(F)C=C3F)C=NN2CC(C)C)NCCN(C)C

InChiKey : IFGWYHGYNVGVRB-UHFFFAOYSA-N

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SynonymsARRY-797;ARRY 797;ARRY-371797;ARRY371797;
Molecular FormulaC22H26F2N4O2
Molecular Weight416.46
Appearanceoff-white solid 
Purity99% Min.
SolubilitySoluble in DMSO, not in water
StorageDry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Shipping ConditionShipped under ambient temperature 
SmileO=C(C1=CC2=C(C=C1OC3=CC=C(F)C=C3F)C=NN2CC(C)C)NCCN(C)C
InChiKeyIFGWYHGYNVGVRB-UHFFFAOYSA-N
InChiInChI=1S/C22H26F2N4O2/c1-14(2)13-28-19-11-17(22(29)25-7-8-27(3)4)21(9-15(19)12-26-28)30-20-6-5-16(23)10-18(20)24/h5-6,9-12,14H,7-8,13H2,1-4H3,(H,25,29)
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ARRY-797 is an oral, selective p38 mitogen-activated protein kinase inhibitor. ARRY-797 is being studied in a Phase 3 trial in patients with lamin A/C-related dilated cardiomyopathy (LMNA-related DCM), a rare, degenerative cardiovascular disease caused by mutations in the LMNA gene and characterized by poor prognosis.

CLINICAL TRIALS

Program: ARRY-797
Phase: 3
Disease: LMNA-related dilated cardiomyopathy
Sponsor: Array

A Study of ARRY-371797 in Patients With Symptomatic Dilated Cardiomyopathy Due to a Lamin A/C Gene Mutation

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