Netarsudil (AR-13324) 2HCl
Catalog No: 1710901
CAS Number: 1253952-02-1
Purity: ≧98.0%
Netarsudil (a.k.a. AR-13324) is ROCK inhibitor with Ki value of 0.2-10.3 nM. It is currently in clinical trials for the treatment of glaucoma and ocular hypertension.
For research use only. We do not sell to patients.
Chemical Information
| Name | Netarsudil (AR-13324) 2HCl |
|---|---|
| Iupac Chemical Name | (S)-4-(3-amino-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate dihydrochloride |
| Synonyms | Netarsudil ; Netarsudil hydrochloride ; AR-13324 HCl ; AR-13324 HCl ; AR13324 HCl ; AR13324 HCl |
| Molecular Formula | C28H27N3O3.2HCl |
| Molecular Weight | 526.45 |
| Smile | O=C(OCC1=CC=C([C@@H](CN)C(NC2=CC3=C(C=NC=C3)C=C2)=O)C=C1)C4=CC=C(C)C=C4C.[H]Cl.[H]Cl |
| InChiKey | LDKTYVXXYUJVJM-FBHGDYMESA-N |
| InChi | InChI=1S/C28H27N3O3.2ClH/c1-18-3-10-25(19(2)13-18)28(33)34-17-20-4-6-21(7-5-20)26(15-29)27(32)31-24-9-8-23-16-30-12-11-22(23)14-24;;/h3-14,16,26H,15,17,29H2,1-2H3,(H,31,32);2*1H/t26-;;/m1../s1 |
| CAS Number | 1253952-02-1 |
| Related CAS | 1422144-42-0 (mesylate) 1254032-66-0 (free base) 1253952-02-1 (HCl) |
Ordering Information
| Packaging | Price | Availability | Purity | Shipping Time |
|---|---|---|---|---|
| Bulk | Enquiry | Enquiry | Enquiry |
| Formulation | Off-white solid to white solid |
|---|---|
| Purity | ≧98.0% |
| Storage | Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years). |
| Solubility | Soluble in DMSO (DMSO : ≥ 100 mg/mL) |
| Handling | Refer to MSDS |
| Shipping Condition | Shipped under ambient temperature as non-hazardous chemical. |
| HS Code | 2934200090 |
Coming soon.
| Targets | |
|---|---|
| Mechanism | |
| Cell study | |
| Animal study | |
| Clinical study |
Not available
Chemical Structure
