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AG 490

Catalog No: 122210
CAS Number: 134036-52-5
Purity: 98% 

AG-490 is a tyrosine kinase inhibitor of JAK2, EGFR, and Neu that belongs to the family of tyrphostins. In acute lymphoblastic leukemia studies the compound has been reported to inhibit JAK2 from B cell precursors. 

For research use only. We do not sell to patients.

Chemical Information

NameAG 490
Iupac Chemical NameN-benzyl-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enamide 
SynonymsTyrphostin B42 
Molecular FormulaC17H14N2O3 
Molecular Weight294.305 
SmileC1=CC=C(C=C1)CNC(=O)/C(=C/C2=CC(=C(C=C2)O)O)/C#N
InChiKeyTUCIOBMMDDOEMM-RIYZIHGNSA-N
InChiInChI=1S/C17H14N2O3/c18-10-14(8-13-6-7-15(20)16(21)9-13)17(22)19-11-12-4-2-1-3-5-12/h1-9,20-21H,11H2,(H,19,22)/b14-8+
CAS Number134036-52-5
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Ordering Information

PackagingPriceAvailabilityPurityShipping Time
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FormulationSolid powder 
Purity98% 
Storage-20 ºC for 3 years 
SolubilitySoluble in DMSO 
Handling
Shipping ConditionShipped under ambient temperature 
HS Code
Coming soon.
Targets
Mechanism
Cell study
Animal study
Clinical study
Not available

Chemical Structure

122210 - AG 490 | CAS 134036-52-5

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